metabolic and endocrine characteristics of indian women with polycystic ovary syndrome
نویسندگان
چکیده
objective: polycystic ovary syndrome (pcos) is one of the most common endocrinological disorders among women of reproductive age and the leading cause of female infertility. this study intends to evaluate the lipid profile, hormonal levels [free t3 (ft3), free t4 (ft4), thyroid stimulating hormone (tsh), insulin, luteinizing hormone (lh), follicle stimulating hormone (fsh), and prolactin] in pcos women from nellore and its surrounding districts of andhra pradesh, india. materials and methods: this cross-sectional study included 80 newly diagnosed pcos women and an equal number of age and body mass index (bmi) matched healthy controls. we used the photometry methods to determine serum glucose levels and the lipid profile. an immunoturbidometry method was employed to measure high sensitive c-reactive protein (hscrp). all hormonal parameters were measured using chemiluminescence immunoassays. insulin resistance was evaluated using the homeostatic model assessment-insulin resistance (homa-ir) method. statistical analysis was done using spss software version 20.0. results: the pcos patients presented statistically higher levels of total cholesterol (tc), triglycerides (tg) and low density lipoprotein cholesterol (ldl-c, p<0.0001) when compared to those of controls. pcos patients had elevated fasting glucose, hscrp, fasting insulin, tsh, lh and prolactin levels (p<0.001). an increased lh/fsh ratio (>1.5) was seen in women with pcos compared with control women. in addition, we observed a direct correlation between fasting insulin with fasting glucose and homa-ir. lh was inversely proportional to bmi. conclusion: the present study showed a higher prevalence of insulin resistance, dyslipidemia, and hypothyroidism in pcos women. furthermore this study showed increased lh concentrations, a higher lh/fsh ratio, and higher prolactin levels in pcos women.
منابع مشابه
Metabolic and Endocrine Characteristics of Indian Women with Polycystic Ovary Syndrome
Objective Polycystic ovary syndrome (PCOS) is one of the most common endocrinological disorders among women of reproductive age and the leading cause of female infertility. This study intends to evaluate the lipid profile, hormonal levels [free T3 (fT3), free T4 (fT4), thyroid stimulating hormone (TSH), insulin, luteinizing hormone (LH), follicle stimulating hormone (FSH), and prolactin] in PCO...
متن کاملMetabolic and Endocrine Characteristics of Indian Women with Polycystic Ovary Syndrome.
BACKGROUND Polycystic ovary syndrome (PCOS) is one of the most common endocrinological disorders among women of reproductive age and the leading cause of female infertility. This study intends to evaluate the lipid profile, hormonal levels [free T3 (fT3), free T4 (fT4), thyroid stimulating hormone (TSH), insulin, luteinizing hormone (LH), follicle stimulating hormone (FSH), and prolactin] in PC...
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Endocrine and metabolic characteristics in polycystic ovary syndrome.
Hirsutism affects 5-25% women, and the condition is most often caused by polycystic ovary syndrome (PCOS). The initial evaluation of hirsute patients should include a thorough medical history, clinical evaluation, and standardized blood samples to diagnose the 5% hirsute patients with rare endocrine disorders. The majority of these examinations can be performed by the patient's general practiti...
متن کاملMetabolic Syndrome and Its Characteristics among Reproductive-Aged Women with Polycystic Ovary Syndrome: A Cross-sectional Study in Northwest Iran
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I-30: Prevalence of Metabolic Syndrome in Women with Polycystic Ovary Syndrome
Background: Metabolic syndrome is a disorder which is composed of several metabolic abnormalities: glucose intolerance, dyslipidemia, obesity and hypertension. PCOS which is characterized by menstrual irregularities and hyperandrogenism, is a common endocrinological disorder in female reproductive age. The prevalence of the syndrome is 5-10%. Insulin resistance is a common feature of the PCOS (...
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عنوان ژورنال:
international journal of fertility and sterilityجلد ۱۰، شماره ۱، صفحات ۲۲-۲۸
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